Monitoring Neuronal Activity

Although most often considered in terms of the generation of action potentials, there are several other electrical, metabolic and ionic correlates of neuronal activity. This book draws together, in a single volume, ten different facets of the activity of nerve cells. There are chapters on the monitoring of extra-cellular unit activity, intracellular voltage and current clamping, patch clamping, video-imaging, in vivo voltammetry, intracerebral dialysis, antibody microprobes, 2-deoxyglucose uptake, intracellular fluorescence and ion-selective electrodes. The techniques described range from the well-established to the experimental. In each case the chapters include up-to-date information, methodological tips and detailed protocols allowing the reader to follow each method in a stepwise fashion. The wide range of techniques in the book should be of interest to neuroscientists, whether concerned with traditional or novel indices on neuronal function.